Repurposing Drugs in Oncology

Growing evidence from epidemiological studies strongly suggests that the increased leukemia rate is likely related to an abnormal immune response to infections early in life.1,2Recent experimental support for the hypothesis of “delayed infection” proposed by Mel Greaves as a cause of childhood leukemia came from Martin-Lorenzo et al. and Swaminathan et al. who demonstrated that exposure of…

While the adult worms are easily removed by a wide range of anthelmintics, as long as the population hasn’t developed resistance to the chosen drug, encysted small strongyle larvae are much more difficult to remove. The cysts protect the parasite within the intestinal wall and prohibit the drugs from reaching the larvae. There are three…

“Antioxidant drugs, such as N-acetyl cysteine (NAC), were effective against all variants both in human lung cells, and in a humanised mouse model. Our study strongly supports the immediate use of available antioxidant drugs, such as NAC, as a general and effective anti-COVID-19 approach.” https://www.biorxiv.org/content/10.1101/2023.01.09.523209v2 “Antioxidant drugs, such as N-acetyl cysteine (NAC), were effective against…

Ivermectin mass drug administration to humans or livestock is a potential vector control tool for malaria elimination. The mosquito-lethal effect of ivermectin in clinical trials exceeds that predicted from in vitro laboratory experiments, suggesting that ivermectin metabolites have mosquito-lethal effect. The three primary ivermectin metabolites in humans (i.e., M1 (3″-O-demethyl ivermectin), M3 (4-hydroxymethyl ivermectin), and…

Professor of Oncology at St George’s Hospital Medical School, London: “At the end of last year I reported that I was seeing melanoma patients who had been stable for years relapse after their first booster (their third injection). I was told it was merely a coincidence and to keep quiet about it, but it became…

Studied minimally? In standard English, no animal trials, no long term trials, no debated scientific papers, … What are the odds of dying? What treatments exist? Cui bono? “ Some of the most crucial revelations focus on how seniors — studied minimally in trials but considered a priority in Florida — are reacting to the vaccine. So far,…